CARBOHYDRATE-BASED CELL ADHESION: ANALYSIS OF SPHEROID FORMATION

Authors

  • Marco Antonio Vieira Macedo Grinet Universidade do Vale do Paraíba
  • Thiago Moreira Pedroso Universidade do Vale do Paraíba
  • Fernanda Roberta Marciano Universidade do Vale do Paraíba

DOI:

https://doi.org/10.18066/revistaunivap.v22i40.1679

Abstract

Carbohydrates are vast constituents of cell surfaces and in many systems where cell adhesion plays a critical role, carbohydrate binding proteins have been shown to bind to cell surface carbohydrates and participate in cell-cell interactions. Jurkat cells are suspension cells that grow in clumps and have 20.7 (± 2.2) hours of population doubling time (PDT). In this experiment, Jurkat cells are studied to compare the effects of wheat germ agglutinin (WGA) lectin, and Maackia amurensis (MAA) lectin, for clumping and spheroid formation studies, as well as carbohydrate analog solutions in ethanol (C2H6O) Ac4ManNAc, and Ac5ManNTGc for concentration effect studies.

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Published

2017-04-27

How to Cite

Grinet, M. A. V. M., Pedroso, T. M., & Marciano, F. R. (2017). CARBOHYDRATE-BASED CELL ADHESION: ANALYSIS OF SPHEROID FORMATION. Revista Univap, 22(40), 834. https://doi.org/10.18066/revistaunivap.v22i40.1679

Issue

Vol. 22 No. 40 (2016): Revista Univap online Edição Especial XX Encontro de Iniciação Científica, XVI Encontro de Pós-Graduação, X INIC Jr e VI INID da Universidade do Vale do Paraíba / ISSN 2237-1753

Section

Resumo - INIC

License

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